BC, BM vs. BC, KS vs. KC, and KM vs. KC (Figure 4A). Commonly enriched pathways included plant-pathogen interaction (map04626), phenylpropanoid biosynthesis (map00940), and MAPK signaling pathway-plant (map04016), all of which are integral to stress perception, signaling cascades, and defense activation. This evidence concerns the gene CALCA and breast cancer.