CALCA and breast cancer: To investigate the gene regulatory responses in the two strawberry cultivars, transcriptome analysis of root tissues under drought stress identified 34,168 DEGs, including 9,665 upregulated and 24,503 downregulated genes Across the four comparison groups, including BS vs. BC, BM vs. BC, KS vs. KC, and KM vs. KC, 4,980, 10,919, 9,891, and 8,378 DEGs were detected, with 1,426, 2,626, 2,362, and 3,251 genes upregulated, and 3,554, 8,293, 7,529, and 5,127 genes downregulated, respectively (Figure 2A).