Immunostaining with anti-afadin, anti-SCGN (Type 2–6 cone BC marker; Puthussery et al., 2010), and anti-PKCα (rod BC marker) revealed that afadin localizes to the dendritic tips, cell bodies, and axons of ON-BCs and at least cell bodies of OFF-BCs (Figure 1D). This evidence concerns the gene AFDN and breast cancer.