Regrettably, CEP3 (AUC = 0.559), CEP7 (AUC = 0.596), CEP17 (AUC = 0.653), P16 (AUC = 0.563) and FISH result (AUC = 0.530) were unsatisfactory in predicting tumour staging. The gene discussed is CDC42EP3; the disease is neoplasm.