Given that YTHDF1-driven CRC stemness critically depends on m6A, we performed methylated RNA immunoprecipitation sequencing (MeRIP-seq) in wild-type CSC28 cells, as well as RNA sequencing (RNA-seq) and ribosome sequencing (Ribo-Seq) in control and YTHDF1-overexpressing CSC28 cells (Fig. 3a), to determine the underlying mechanism. Here, YTHDF1 is linked to colorectal carcinoma.