In contrast, ApcMin/+Ythdf1cKo mice presented significant reductions in tumor number (P = 0.037) and tumor load (P = 0.033) (Fig. 2g), with reduced cell proliferation (P < 0.0001) and enhanced apoptosis (P = 0.0006), as shown by Ki67 and TUNEL staining, respectively (Fig. 2h). The gene discussed is MKI67; the disease is neoplasm.