YTHDF1 and infectious otitis media: Lgr5-specific Ythdf1-KI mice presented accelerated ApcMin/+ (P < 0.05) and AOM/DSS (P < 0.05)-induced colorectal tumorigenesis, whereas Lgr5-specific Ythdf1 knockout in ApcMin/+ mice inhibited tumorigenesis (P < 0.01).