Univariate logistic regression identified CSF3R mutation as a strong negative predictor of CR (OR 0.34; 95% CI, 0.17–0.65; p = 0.001), along with myelodysplasia‐related changes (AML‐MRC), R/R status, TP53, ASXL1, RUNX1, monosomy 17 or 17p abnormalities, and complex karyotypes. The gene discussed is CSF3R; the disease is acute myeloid leukemia.