In the peripheral stimulation test results, although screening markers of hypercortisolemia were overall similar between the two groups, baseline serum cortisol at the time of the stimulation test was lower in the DDAVP group (14.1 mcg/dL [12.4, 16.8]) compared to the CRH group (18.7 mcg/dL [15.5, 24.7], p < 0.001), while baseline ACTH levels were similar between the two groups (47.5 pg/mL [27.5, 58.0] in the DDAVP group vs. 48.5 pg/mL [33.4, 58.6] in the CRH group, p = 0.73). Here, POMC is linked to adrenal gland hyperfunction.