So, the correlation described in the current study could represent either evidence of the participation of podoplanin in platelet activation, in alignment with Lavallé et al. [8], who demonstrated that podoplanin-expressing APL blasts can activate platelets, or a yet unknown association between podoplanin and CD40L in another hematopoietic compartment. Here, CD40LG is linked to acute promyelocytic leukemia.