Both P-selectin (7194 pg/mL versus 11,220 pg/mL; p-value = 0.003) and CD40L levels (100.4 pg/mL versus 196.6 pg/mL; p-value = 0.002) were significantly lower in APL patients compared to those with other AML subtypes (Figure 2A,B). This evidence concerns the gene CD40LG and acute promyelocytic leukemia.