TPK1 and neuroblastoma: Moreover, active ACAT1 acetylates pyruvate dehydrogenase, reducing its activity and potentially decreasing the efficiency of OXPHOS with consequences for the Warburg effect and tumour growth [42], while a recent study described the chlorogenic acid‐induced downregulation of ACAT1 leading to NB differentiation via the metabolic ACAT1‐TPK1‐PDH pathway restricting tumour growth [29], showcasing significant therapeutic promise.