The glycolytic genes, HK2, GAPDH and ENO1, were chosen as they mediate early, mid and final stages of glycolysis respectively, and all three ketolytic genes BDH1, OXCT1 and ACAT1 were analysed for MYCN amplification, survivability and tumour stage progression in three NB datasets. The gene discussed is HK2; the disease is neuroblastoma.