DM alone did neither result in significant changes in renal fibrosis (Fig. 1a,b), nor in changes in markers of kidney injury (Kidney injury molecule 1, KIM1; Fig. 1d), NGAL (a tubular injury marker, Fig. 1e) or urinary protein to creatinine ratio (UPCR, Fig. 1f), although kidney weight was significantly increased (Fig. 1c). This evidence concerns the gene HAVCR1 and renal fibrosis.