LCN2 and renal fibrosis: DM alone did neither result in significant changes in renal fibrosis (Fig. 1a,b), nor in changes in markers of kidney injury (Kidney injury molecule 1, KIM1; Fig. 1d), NGAL (a tubular injury marker, Fig. 1e) or urinary protein to creatinine ratio (UPCR, Fig. 1f), although kidney weight was significantly increased (Fig. 1c).