Among the 134 independent loci for aortic stenosis (Supplementary Table 12), we re-identified all of the 23 previously reported loci for calcific aortic stenosis, with the sole exception of a locus near HMGB1 from ref. 19 and 29 of the 32 loci reported from ref. 7 (Supplementary Table 9). This evidence concerns the gene HMGB1 and aortic stenosis.