PTPRC and amyloidosis: Here, we found GPR120 highly expressed in integrin α M (ITGAM, also known as CD11b)-positive cells surrounding amyloid plaques44 (amyloid plaques-associated CD11b+GPR120+ cells), comprising mainly activated microglia (CD11b+Iba1+ cells), macrophages45 (CD11b+CD45+ cells), and a small fraction of monocyte-derived macrophages (CD11b+CD14+ cells) (Fig. 2a,c and Extended Data Fig. 3).