To functionally evaluate the impact of common DEG in EVI1+ iKMT2A-r and human AML we identified a single KMT2A-rearranged (KMT2A-MLLT1+) cell line OCI-AML4 that expresses high levels of EVI1 without any 3q26 locus alteration (https://depmap.org/portal/ & Fig. 6A)54. The gene discussed is MLLT1; the disease is acute myeloid leukemia.