While no differential Mac-1/Gr-1 or c-Kit expression was detected, faster disease development in the recipients of TPO-exposed MPP1 was associated with an increased proportion of FcγRII/III- cells (1.7% ± 0.5 vs 6.7% ± 1.2, p = 0.0076) (Supplementary Fig. 2I–L) with tumor cells expressing high levels of Evi1 in most animals (Fig. 2H). This evidence concerns the gene TPO and neoplasm.