GSEA and over-representation analysis (ORA) on the common DEG between human and mouse AML revealed enrichment of pathways linked to several “AML” signatures, “Haematopoietic stem cells” and targets of HOXA9 (“TAKEDA Targets of NUP98-HOXA9 fusion”) (Supplementary Fig. 5E). The gene discussed is HOXA9; the disease is acute myeloid leukemia.