MECOM and acute myeloid leukemia: Three genes, MECOM, IL12Rβ2 (interleukin 12 receptor subunit beta 2), INPP4B (inositol polyphosphate-4-phosphatase type II B) were significantly higher expressed in mouse Evi1+ iKMT2A-MLLT3 AML and all human EVI1+ AML datasets (Fig. 5C, Supplementary Data file 9).