Additionally, HKLM- or LPS-treated USP11-KO CRC cells exhibited markedly lower proliferation rates than corresponding control cells (Fig. 5E, F, USP11-KO HCT-15 treated with HKLM or LPS vs. Ctrl HCT-15 treated with HKLM or LPS; Fig. 5G, H, USP11-KO HT-29 treated with HKLM or LPS vs. Ctrl HT-29 treated with HKLM or LPS). The gene discussed is USP11; the disease is colorectal carcinoma.