USP11 and colorectal carcinoma: Similarly, in transwell migration assays, USP11-KO CRC cells treated with HKLM or LPS demonstrated significantly decreased number of cells compared to Ctrl CRC cells treated with HKLM or LPS (Fig. 5C, USP11-KO HCT-15 treated with HKLM or LPS vs. Ctrl HCT-15 treated with HKLM or LPS; Fig. 5D, USP11-KO HT-29 treated with HKLM or LPS vs. Ctrl HT-29 treated with HKLM or LPS).