Given the complexity of tumor-infiltrating immune cells, which include various types such as Myeloid-Derived Suppressor Cells (MDSCs), neutrophils, macrophages, and regulatory T-cells (Tregs),33 the authors employed the CIBERSORT algorithm and the TISIDB database to assess the correlation between SIGLEC9 expression and immune cell composition in the TME. Here, SIGLEC9 is linked to neoplasm.