TNFRSF10B and neoplasm: Here, we demonstrated that tuvusertib treatment increased tumor cell lysis by HD and PCa patient NK cells and is associated with increased surface expression of ULBP-1, an NKG2D ligand [36], on DU145 cells and the death receptor TRAIL-R2 [10] on both DU145 and 22Rv1 cells (Fig. 2C,D).