Associations weakened with increasing age at diagnosis, consistent with a 12‐year prospective study of 250,000 to 300,000 individuals reporting stronger associations between sociodemographic and lifestyle factors and early‐onset versus late‐onset dementia, whereas apolipoprotein E ε4 allele carriage showed stronger associations with late‐onset cases.25 The gene discussed is APOE; the disease is dementia.