NFKB1 and endothelial dysfunction: – Upregulates SIRT1/AMPK axis to inhibit oxidative injury– Induces endothelial dysfunction– Increases SIRT1 expression and decreases NF‐κB– Activates SIRT1/PGC‐1a and Bcl‐2/Bax pathways, exerting antiapoptotic effects