Silencing CHST6 led to a significant downregulation of EMT-related genes, including ZEB1, ZEB2, VIM, TWIST1, SNAIL, FN1, N-CAD, E-CAD, CTGF, and COL1A2, indicating that CHST6 may contribute to fibroblast activation and EMT processes in IPF [Figs. 7(i) and 7(j)]. This evidence concerns the gene CHST6 and idiopathic pulmonary fibrosis.