MTOR and viral infectious disease: It has been shown that BEZ235, an inhibitor of PI3K/mTOR, acts as a modulator of viral production following viral infection and inhibits viral replication by decreasing PI3K and mTOR levels, as well as phosphorylation products, blocking transient induction of c-Myc, and decreasing the homeostasis of the pathway for 4E-BP-1 and P85 phosphorylation (Yu et al., 2022).