ERBB2 and digestive system neoplasm: Next-generation sequencing (NGS, detecting instrument MGISEQ-2000, coverage 30 genes of gastrointestinal tumors, analysis pipeline Read1 Q30, amplification cutoff 1%) revealed microsatellite stability, HER2 amplification (copy number: 14.3), TP53 p.D57* (variant allele frequency (VAF) 14.5%), ERBB2 p.A270S (VAF 95.9%), and wild-type KRAS, NRAS, and BRAF.