AFP and neoplasm: Clinical complete response, defined as sustained radiological complete response and tumor marker normalization (AFP <7 ng/mL and PIVKA-II <40 mAU/mL) for at least four weeks, has been identified as a strong predictor of pathological complete response in recent studies.15) In our case, although the tumor markers normalized early, there was regrowth of the PALN during treatment, indicating the emergence of resistant tumor clones.