Moreover, Gonzalez-Gronow et al. (2003) demonstrated that VDAC (not isoform specific), expressed on the cell surface of the human neuroblastoma SK-N-SH cell line, has been shown to promote the activation of plasminogen (Pg) through the binding of tissue-type plasminogen activator (t-PA) (Gonzalez-Gronow et al., 2003; 2013). The gene discussed is PLAT; the disease is neuroblastoma.