Resectable tumors from head and neck squamous cell carcinoma (n=36) (HNSCC), breast cancer (n=37) (BC), and colorectal cancer (n=36) (CRC) were evaluated for CD47 expression by immunohistochemistry (IHC), two multiplex immunofluorescence panels were used to characterize TAM markers and T cell markers. The gene discussed is CD47; the disease is colorectal carcinoma.