The mean beclin-1 and Bcl-2 histoscore values and beclin-1+ and Bcl-2+ cell percentages were significantly higher in DLBCL than in non-tumor control samples (beclin-1: 4.6 ± 1.3 vs 3.8 ± 1.0, p = 2.0e-02; and 62.9% ± 21.7 vs 47% ± 19, p = 4.0e-02, respectively; Bcl-2: 4.9 ± 1.2 vs 4.1 ± 2.1, p = 3.0e-01; and 55.8% ± 13.5 vs 39.0% ± 7.3, p = 0.05, respectively) (Figures 4C, D). The gene discussed is BECN1; the disease is diffuse large B-cell lymphoma.