The IHC results obtained in an independent DLBCL cohort confirmed the bioinformatics findings: increased expression of beclin-1 (autophagy factor) and Bcl-2 (anti-apoptosis factor), and higher infiltration of CD86+ cells than CSF1-R+ cells in the DLBCL microenvironment. The gene discussed is CSF1R; the disease is diffuse large B-cell lymphoma.