KEGG pathway analysis further indicated involvement in the PPAR signaling pathway, steroid hormone biosynthesis, Rap1 signaling pathway, TRP channels in inflammatory mediator regulation, Ras signaling pathway, chemical carcinogenesis (including DNA adduct formation and receptor activation), central carbon metabolism in cancer, and the cAMP signaling pathway, among other key pathways (Figure 1C). The gene discussed is PPARA; the disease is cancer.