Chemokines and cytokines such as CSF2, CCL12, CCL20, IL1B, and CXCL3/5/6 are significantly upregulated in the tumor microenvironment, indicating that the body is extensively recruiting and activating myeloid immune cells (Arnone et al., 2021; Song et al., 2024). Here, CXCL3 is linked to neoplasm.