At day 10 after SNI, when the nociceptive sensitization and memory deficit comorbidity had been established, microinjection of IGF‐1 (1 μg/μL, 0.5 μL) into the contralateral dorsal DG in mice (to the injury), on day 10 after SNI, and then daily for 4 days, significantly increased the tactile threshold (Figure 4A) and the dynamic score (Figure 4B) to brush stroke in the ipsilateral hind paw at day 11–16, and on the novel object recognition index (Figure 4C) at day 11 after SNI. Here, IGF1 is linked to Stroke.