KEGG pathway analysis showed that DEGs were significantly enriched in “neuroactive ligand–receptor interaction,” “PI3K–Akt signalling pathway,” “calcium signalling pathway,” “cAMP signalling pathway,” “MAPK signalling pathway,” “Alzheimer disease” and “GABAergic synapse,” especially in “neuroactive ligand–receptor interaction,” where up to 67 DEGs were enriched. The gene discussed is AKT1; the disease is early-onset autosomal dominant Alzheimer disease.