GO enrichment analysis of DEGs was significantly enriched in “signalling receptor activator activity” and “receptor ligand activity.” Moreover, KEGG annotation indicated that the “PI3K–Akt signalling pathway,” “cAMP signalling pathway,” “calcium signalling pathway” and “MAPK signalling pathway,” which are closely related to neurodegenerative diseases, were involved. This evidence concerns the gene AKT1 and neurodegenerative disease.