KPNA2 and viral infectious disease: KPNA2 is also implicated in a range of other cellular processes, including cell differentiation, proliferation, apoptosis, transcriptional regulation, immune response, and viral infection [6], and has also been established to play roles in the subcellular localization of key DNA damage response (DDR) proteins, with the expression of these proteins in the cytoplasm being associated with that of KPNA2 [7].