CP-GEP included eight target genes associated with tumor development (i.e., MLANA, GDF15, CXCL8, LOXL4, TGFBR1, ITGB3, PLAT, and SERPINE2) and two housekeeping genes in combination with clinicopathological variables, age, and Breslow thickness.<h4>Results</h4>The median age was 57 years old, and 51.4% were female. This evidence concerns the gene SERPINE2 and neoplasm.