At increasing effector-to-target ratios, PBMCs from both M02 and M10 (Fig. 2c), and M04, M05, M07, and M08 (Supplementary Fig. 2) lysed SKOV3 tumor cells engineered to express MUC16 (SKOV3-Muc16ecto) and OVCAR3 cells that endogenously express MUC16/CA125 (Fig. 2d). The gene discussed is MUC16; the disease is neoplasm.