In line with the bulk qPCR analysis (Fig. 1k), the expression of common transcriptional subtype markers of SCLC (A/N/P/Y) did not differ between RP and RPC tumors, and ASCL1 seemed to be the predominantly expressed transcription factor in both genotypes (Supplementary Fig. 2d). This evidence concerns the gene ASCL1 and small cell lung carcinoma.