The Slitrk2 T312A mutation identified in patients with neurodevelopmental disorders appears to exert phenotypes similar to Slitrk2 V89M [17]; thus, it would be extremely interesting to use Slitrk2T312A-cKI mice to examine whether this mutation yields similar or distinct alterations in the synaptic properties identified in the current study. The gene discussed is CHKA; the disease is neurodevelopmental disorder.