To assess anti-tumor immune memory, MC38-Luc cells were re-inoculated into the mice 75 days after having previously achieved CR after combined IL-15, NIR-PIT, and anti-PD-1 mAb (n = 9, Supplementary Fig. S5) and combination therapy of IL-15 and NIR-PIT (n = 2, data not shown). Here, IL15 is linked to neoplasm.