SH2B1 and non-small cell lung carcinoma: Furthermore, SH2B1 depletion suppressed glucose consumption (Figure 1A) and lactate production (Figure 1B), reduced ECAR (Figure 1C), but raised OCR (Figure 1D) in NSCLC cells; however, we observed opposite results in the SH2B1‐overexpressed group (Figure 1A–D).