Although an initial positive result for SMA raised concerns about autoimmune hepatitis, several findings argued against this condition: a subsequent negative SMA result within one week, rapid clinical improvement without immunosuppressive therapy, polyclonal hypergammaglobulinemia rather than isolated IgG elevation, negative ANA, absence of autoimmune history, and the presence of acute EBV infection - a known cause of viral hepatitis [22]. The gene discussed is BTG3; the disease is autoimmune hepatitis.