IL6 and Increased total leukocyte count: Subsequent laboratory investigations demonstrated severe systemic infection manifesting as leukocytosis (WBC 18.2 × 109/L) with neutrophil predominance (94.5%), accompanied by markedly elevated inflammatory markers including CRP 102.7 mg/L, PCT 58.7 ng/mL, interleukin-6 (IL-6 1,013.9 pg/mL), and (1,3)-β-D-glucan (221.37 pg/mL).