As 13 participants with KICS and KS formed the most abundant group of those with KAD and KS, analyses of their KS lesions as compared to those with KS alone had decreased expression of CCR4 (log2FC= −1.1, padj= 0.04), MS4A1 (log2FC= −1.6, padj= 0.002), KIR3DL1 (log2FC= −1.5, padj= 0.04), which are genes associated with immune cell activity. This evidence concerns the gene KIR3DL1 and Kaposi's sarcoma.