Through violin plots, we found that in endothelial cells, the mRNA expression of LAMC1, RBMS2, MYO1C, TMOD3, APOL3, and LRP10 in the F_AD (female with AD pathology) (APOE ε3/ε4 or ε4/ε4) group was much higher than other groups. The gene discussed is LAMC1; the disease is Alzheimer disease.