Out of the 31 genes suggested as modifiers for SCD phenotypes, 11 genes (ACKR1, AGER, FCER1A, HLA-A, HLA-DQB1, HLA-DRB1, HLA-G, NOTCH4, RRM1, STIM1, and TRIM5) showed the ability to interact with a total of 114 distinct drug molecules. This evidence concerns the gene ACKR1 and Schnyder corneal dystrophy.