To our knowledge, this is the first reported case of LMNA::NTRK1-rearranged spindle cell neoplasm with three key novel features: (1) pigmentation (dendritic pigment-containing stromal cells), (2) multiple local recurrences (two episodes within 27 months), and (3) fibrosarcoma-like malignant transformation. This evidence concerns the gene NTRK1 and spindle cell neoplasm.