Patients with mechanical complications exhibited distinct profiles: lower systolic blood pressure (115.9 vs. 123.5 mmHg, p = 0.001), higher STEMI prevalence (60.6% vs. 44.1%, p < 0.001), advanced Killip class III-IV (22.5% vs. 13.3%, p < 0.001), and biomarker evidence of intense inflammation (elevated WBC, neutrophil%, hs-CRP), myocardial injury (higher cTnT, NT-proBNP), and metabolic derangements (hypoalbuminemia, hyperkalemia). This evidence concerns the gene TNNT2 and Hypoalbuminemia.