Immunohistochemical: Cytokeratin (CK) (++), Ki67 (approximately 60%+), Synaptophysin (Syn) (+), Chromogranin A (CgA) (-), CD56(-), D2-40 (Vascular negative), CD31 (Vascular positive), Insulinoma-Associated Protein 1 (INSM1) (-), Somatostatin Receptor 2A (SSTR2A) (-), Alpha-Thalassemia/X-Linked Intellectual Disability Syndrome Gene (ATRX) (+), P53 (Positive at different intensity), Thyroid Transcription Factor-1 (TTF-1) (-), Trypsin (+++), B-Cell Lymphoma/Leukemia 10 (Bcl10) (-), CD10 (-), β-catenin (membrane positive), AFP (partially positive). The gene discussed is INSM1; the disease is alpha thalassemia spectrum.