SDCBP2 and cancer: We then assessed the impact of SDCBP2 on overall survival (OS) in various cancers (Figures 2C, D) and found that SDCBP2 is a prognostic risk gene only in LUAD (HR = 1.661, 95%CI: 1.241-2.222, P < 0.001), while it is a prognostic protective gene in BLCA and KIRC (HR = 0.725, 95%CI: 0.540-0.973, P = 0.032; HR = 0.711, 95%CI: 0.527-0.959, P = 0.026).