Once PD-L1 mRNA is made, its half-life can be prolonged by lncRNA SWI/SNF complex antagonist associated with prostate cancer 1 (SChLAP1), which recruits AU-rich element RNA-binding factor 1 (AUF1) to the 3′-UTR and shields the transcript from degradation, thereby elevating steady-state protein levels and fueling tumor growth (71). This evidence concerns the gene CD274 and neoplasm.