NLRP3 and atrial fibrillation: Next, the prognostic significance of serum NLRP3 inflammasome and occludin was further investigated using multivariate analysis, incorporating the following variables: age, atrial fibrillation, HT, TOAST classification, infarct volume, NIHSS score on admission, fibrinogen, LDL-C, fasting blood glucose, leukocyte count and neutrophil percentage.