Table 2 demonstrates a significant variation in serum levels of NLRP3 inflammasome and occludin among AIS patients based on stroke severity (p < 0.001). Specifically, patients in the severe group had significantly higher serum levels of NLRP3 inflammasome and occludin compared to those in the mild group (NLRP3 inflammasome: 129.53 (91.14–189.99) pg/mL vs. 56.34 (37.84–77.17) pg/mL, p < 0.001; occludin: 280.27 (211.30–306.57) ng/mL vs. 83.43 (54.57–161.92) ng/mL, p < 0.001). Here, OCLN is linked to Stroke.