In terms of tumors, Studies have shown that SGPP2 can promote the development of tumors such as lung adenocarcinoma and gastric cancer, and its expression level is positively correlated with clinicopathological features such as lymph node metastasis, suggesting that SGPP2 may be an important indicator for assessing tumor prognosis [46–48]. This evidence concerns the gene SGPP2 and lung adenocarcinoma.