Using data from TCGA, CPTAC-PAAD, QCMG-PAAD, and METABRIC-BRCA, we stratified patients with pancreatic cancer (PAAD) and breast cancer (BRCA) into top and bottom quartiles of ACVR1B expression and then performed gene set enrichment analysis (GSEA) using EMT and cancer-associated gene signatures. The gene discussed is ACVR1B; the disease is familial pancreatic carcinoma.