DCC and cancer: We downloaded the coexpression data of netrin1 and its receptors and transcription factors, which were located within 1-kb upstream and downstream regions, as well as chromatin remodeling factors in TCGA cancers from ChIPBase v2.042 These included 20 NTN1 modifiers (Fig. 6a), 14 DSCAM modifiers (Fig. 6b), 6 DCC modifiers (Fig. 6c), 28 NEO1 modifiers (Fig. 6d), 29 MCAM modifiers (Fig. 6e), 28 UNC5A modifiers (Fig. 6f), 40 UNC5B modifiers (Fig. 6g), 27 UNC5C modifiers (Fig. 6h), and 8 UNC5D modifiers (Fig. 6i).