探索应用阿扎胞苷联合来那度胺治疗伴TP53突变的骨髓增生异常肿瘤(myelodysplastic neoplasms, MDS)患者的有效性和安全性;初步探索治疗有效的潜在机制。. This evidence concerns the gene TP53 and myelodysplastic syndrome.